Wheelchair-bound middle school student Jamie Grimm's recent victory in the Planet's Funniest Kid Comic Contest leads to a television sitcom based on his life, but being the star of the show forces him to balance his newfound success with the responsibilities of being a good friend.

Twelve-year-old Derek wants to train his pet monkey to help Umberto, a new student who uses a wheelchair, but Umberto would rather steal Derek's cartoon ideas.