Building on the events of Frank Herbert's final novel, Chapterhouse of Dune, a ship of escaped refugees uses genetic technology to revive talented figures from the world's past in order to safeguard their survival.

A group of refugees escapes on a ship into the uncharted reaches of the galaxy, seeking safety with the assistance of Paul Muad'Dib and Lady Jessica, revived with the help of genetic technology, while avoiding the diabolical traps of the Enemy.